Wednesday 17 February 2016

Scientists Close In On Zika Link With Paralysis

19:23, UK, Wednesday 17 February 2016
Busy ward at University Hospital in Cali, Colombia
Scientists say they are on the verge of confirming that Zika is the cause of the paralysing condition Guillain-Barre.
Colombian researchers told Sky News they have detected the virus lingering in the blood of five patients with the syndrome.
Such persistent infection can trigger the chain reaction that leads the immune system to go rogue and attack the nerves, causing the paralysis.
With every additional case the cause becomes more certain, according to Dr Andreas Zea, a  neurologist in Cali who is closely involved in the joint Colombian-American research project.
"In my mind it is related to Zika," he said.
Zika virus
"It is terrible. It’s a mosquito. Only one bite and 15, 20 days later you are going to be in intensive care. These patients have families."
We tracked down the family of Alix Mulato.
A month ago the 45-year-old was a stout sugar cane worker.
But he contracted Zika and then developed Guillain-Barre.
Now he is paralysed, brain damaged and beyond medical help.
His wife, Elizabeth Ramos, showed us video of him lying under a net in intensive care.
"My husband was a very healthy man," she said.
"For our family it is a complete tragedy. We have been together a long time, with our sons.
"We don't understand. Why him? Why him?"
In Cali’s University Hospital we found Sandra Tamayo, another patient who developed Guillain-Barre shortly after contracting Zika.
Her face is paralysed.
She can't blink, and struggles to move her mouth.
Zika virus
She wept as she told me that she hasn't allowed her daughter to visit since being admitted two weeks ago for fear of frightening her.
"The situation is terrible, really terrible," she said.
"I can't express anything. If I am smiling inside I can't express it.
"It's like wearing a mask."
The hospital would normally see a couple of Guillain-Barre cases a month.
But that has doubled in the wake of the Zika epidemic.
And with Cali expecting another 20,000 patients with the virus over the next four months, doctors are making preparations for the numbers with Guillain-Barre to rise by 10 times.
"It will be difficult to get enough places in intensive care units for the people who will need it in the next months," Dr Zea warned.
He’s also concerned that immunoglobulin, the antibody treatment derived from human blood donations, will be in short supply as demand increases across the region.
Eight countries in South and Central America have reported a rise in Guillain-Barre.
The World Health Organisation has warned that if the link with Zika is confirmed, the human and social consequences will be staggering. 
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